Gene Mapping Centre

Gene mapping in the mouse system

We have also set up gene mapping in the mouse system (Schalkwyk  et al 1999). We have so far mapped twelve mouse phenotypes (Bittner et al 1999,  Graw et al 1999, further data unpublished). We have also mapped individual confirmed mutants from the DHGP funded ENU-mouse screen from the GSF (Hrabe de Angelis et al 2000). In addition, two projects for polygenic traits in the mouse involving quantitative loci, one allergy-related (Daser et al 2000) and one with a DNA-methylation phenotype (Dr. J. Walther, Berlin), have been completed. Each comprised about 200 backcross animals.